Anesthesiology
Mahdi Mirhamidi; Atefeh Asadi; Mahbobeh Nematshahi; Mohammad nematshahi; Manijeh Yousefi; Davood Sourosh; Ali Tajabadi; Adeleh Abdolalizadeh; hossein fahimi
Volume 27, Issue 2 , July and August 2020, , Pages 295-302
Abstract
Abstract:Thiopental Sodium is a commonly used drug in anesthesia, but it is not ideal because barbiturate is prohibited in acute and allergic porphyria, and is not recommended in asthmatic and hypovolemic patients. Propofol is the newest drug in anesthesia due to its rapid onset, short duration of action, ...
Read More
Abstract:Thiopental Sodium is a commonly used drug in anesthesia, but it is not ideal because barbiturate is prohibited in acute and allergic porphyria, and is not recommended in asthmatic and hypovolemic patients. Propofol is the newest drug in anesthesia due to its rapid onset, short duration of action, anti-nausea and a feeling comfort after use, its consumption is increasing. It is also safe in porphyry and asthma. This study compares the use of sodium antiproliferative drug propofol to reduce the need for opiate.Analysis Method:This study was conducted on 173 patients admitted to Sabzevar Hospital. Patients were randomly divided into two study and control groups. Anesthesia induction was performed in the study group with propofol 2. 2 kg / mg and with thiopental sodium 5 kg / mg, in both groups, blood pressure and heart beats were measured before and after induction and minutes 1, 5 and 11 after intubation. Within 1-2-3-4 hours after operation with a pain control chart, the intensity of the pain was checked and the data were recorded.Findings:In the propofol group at the 4th hour, 44 individuals feel mild pain, and 9 had moderate, but severe pain was not reported(P=0/44). In the thiopental group at the fourth hour, 53 patients feel mild pain, 11 had moderate and 5 had severe pain.(P=0/44)Conclusion:Propofol increases the threshold of postoperative pain, so it can be a good alternative to thiopental. Keyword: Thiopental, Propofol, Opiate